Nordmark Collagenase AF-1 GMP Grade


≥ 2,000 U (PZ)




Collagenase AF-1 GMP Grade is derived from C. histolyticum using a production process completely free of any animal based components. Thus, any risk of transmission of potential animal-derived pathogens is excluded. This highly purified collagenase, often in combination with Neutral Protease AF GMP Grade, is suitable for the dissociation of sensitive cells from several tissues, such as pancreas, liver and dental pulp. It has been shown to be highly effective for the isolation of islets of Langerhans from human pancreas intended for transplantation.

Collagenase AF-1 GMP can be used for several cell isolations, but is commonly used for human islet isolation.

PZ activity (WŁnsch) ≥ 3.00 U/mg.


For information and samples please contact us at:

Crescent Chemical Co., Inc.

2 Oval Dr.

Islandia, NY 11749

(631) 348-0333