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Neutral Protease
CRESCENT CHEMICAL CO., INC. supplies COLLAGENASE NB , NEUTRAL PROTEASE NB and CLOSTRIPAIN NB enzymes in the Americas. Nordmark Collagenase, Neutral Protease and Clostripain are enzymes that are used for tissue dissociation and cell isolation for clinical and research applications. The use of a cell type specific Collagenase NB, Neutral Protease NB ensures the isolation of vital cells with the highest yield. Nordmark is the world's largest collagenase producer. Products are manufactured under strict pharmaceutical regulations which guarantees stringent quality control, reliable lot-to-lot consistency and excellent product performance. TSE safety of the fermentation product has been certified by the European Authorities, EDQM and the supplier’s certificate of origins.

ANIMAL FREE NEUTRAL PROTEASE AF GMP GRADE
NORDMARK ANIMAL FREE GMP GRADE NEUTRAL PROTEASE- WORLD'S FIRST Neutral Protease AF GMP Grade is derived from C. histolyticum using a production process completely free of any animal based components. Thus, any risk of transmission of potential animal-derived pathogens is excluded. This purified metalloprotease is suitable for the dissociation of tissue in clinical applications. For especially gentle cell isolation it is recommended to use Neutral Protease AF GMP Grade in combination with highly purified Collagenase AF-1 GMP Grade (Cat. No. N0003554).

GMP NEUTRAL PROTEASE NB
NORDMARK GMP NEUTRAL PROTEASE - HIGHEST QUALITY AND SAFETY FOR CLINICAL APPLICATIONS Metalloprotease suitable for tissue dissociation applications. For cell isolation Neutral Protease NB GMP Grade is used in combination with purified Collagenase NB 1 GMP Grade (Cat. no. N0002937) or Collagenase NB 6 GMP Grade (Cat. no. N0002779) for applications which have to meet GMP requirements like tissue engineering and transplantation into humans.

NEUTRAL PROTEASE NB
NORDMARK NEUTRAL PROTEASE NB - FIRST CHOICE FOR HIGH YIELD AND VIABLE CELLS Metalloprotease suitable for tissue dissociation applications. For cell isolation Neutral Protease NB is used in combination with purified Collagenase NB 1 Premium Grade (Cat. no. S1745503) as well as Collagenase NB 4 Standard Grade (Cat. no. S1745401) or Collagenase NB 8 Broad Range (Cat. no. S1745601). For research use only. If cells are intended for transplantation into humans, Neutral Protease NB GMP Grade (Cat. no. N0002936) is recommended.

NEUTRAL PROTEASE NB HIGH ACTIVE GRADE
NORDMARK NEUTRAL PROTEASE NB HIGH ACTIVE GRADE - FIRST CHOICE FOR HIGH YIELD AND VIABLE CELLS Metalloprotease suitable for tissue dissociation applications. For cell isolation Neutral Protease NB High Active Grade is used in combination with highly purified Collagenase NB 1 Premium Grade (Cat. no. S1745503), Collagenase NB 4 Standard Grade (Cat. no. S1745401) or Collagenase NB 4G Proved Grade (Cat. no. S1746501).

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