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NB 1 Premium Grade
Cat. No. 17455.03
Pack Size ≥ 2,000 PZ U/Vial
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- Chromatographically highly purified
- Class l and ll collagenases
- Use in combination with NB Neutral Protease
- PZ activity * ≥ 3.0 U/mg lyophilisate
- Largely free of clostripain, trypsin-like proteases
- Endotoxins ≥ 10 EU/mg lyophilisate
- Collagen characterization
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- Isolation of pancreatic islets
- Use in combination with Neutral Protease NB
- Collagen characterization
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NB 1 GMP Grade
Cat. No. 17542.01
Pack Size ≥ 2,000 PZ U/Vial |
- Enzymatic properties see NB 1 Premium Grade
- Manufactured according to Intl. cGMP guidelines
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- Isolation of pancreatic islets for transplantation into humans
- Use in combination with Neutral Protease NB GMP Grade
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AF-1 GMP Grade
Cat. No. 17457-01
Pack Size ≥ 2,000 PZ U/Vial |
- Chromatographically highly purified
- Class l and ll collagenases
- Very low levels of endotoxins
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- Isolation of pancreatic islets sensitive liver, dental pulp cells
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NB 4 Standard Grade
Cat. No. 17454.01/ 1 g
Cat. No. 17454.02/ 500 mg
Cat. No. 17454.03/ 5 g |
- Class l and ll collagenases and a balanced ratio of proteolytic activities
- PZ activity* ≥ 0.1 U/mg lyophilisate
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- Isolation of various cell types including neuronal and endothelial cells, chondrocytes, adipocytes epithelial cells, stem cells, gangliocytes and periodontal cells
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NB 4G Proved Grade
Cat. No. 17465.01/ 500 mg
Cat. No. 17465.02// 1 g
Cat. No. 17465.03/ 5 g |
- Class l and ll collagenases as well as a balanced mix of neutral protease, clostripain, and tryptic activities
- PZ act.* ≥ 0.18 U/mg lyophilisate
- Fuction tested for cell isolation
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- Isolation of adipocytes, fibroblasts hepatocytes, chondrocytes, stem cells, frog oocytes, mastocytes and tumor cells
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NB 5 Sterile Grade
Cat. No. 17459.03 / 1 g |
- Enzymatic properties see NB 4
- Sterile according to European req. For medicinal prods. (Pharm. Eur.)
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- Application fields see NB 4
- Sterile and ready to use
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NB 6 GMP Grade
Cat. No. 17458.03/ 1 g
Cat. No. 17458.04/ 100 mg |
- Enzymatic properties see NB 4
- Aseptic production according to
- European req. for medicinal prods.(Pharm. Eur.)
- Manufactured according to Intl. cGMP guidelines
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- Application fields see NB 4
- Production of cell as well as tissue engineering for transplantation into humans
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NB 8 Broad Range
Cat. No. 17456.01/ 250 mg
Cat. No. 17456.02/ 1 g |
- Class l and ll collagenases and reduced levels of clostripain, trypsin-like activities and neutral protease
- PZ act.* ≥ 0.9 U/mg lyophilisate
- Endotoxins ≥ 100 EU/mg lyophilisate
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- Isolation of cardiomyocytes, porcine hepatocytes, rodent pancreatic islets tumor and thyroid cells
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NB Neutral Protease
Cat. No. 30301.11/ 50 U (DMC)
Cat. No. 30301.12/ 100 U (DMC) |
- Chromatographically purified neutral protease.
- Activity (DMC assay) ≥ 0.50 U/mg
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- Tissue dissociation
- Cell isolation in combination with Collagenase NB
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NB Neutral Protease
High Active Grade
Cat. No. 30302.02/ 80 U (DMC) |
- Chromatographically purified and contains an increased proteolytic activity
- Largely free from collagenolytic activity (PZ U)
- Endotoxin level is very low
- Activity (DMC assay) ≥ 4.00 U/mg
- Endotoxin ≥ 50.0 EU/mg
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- Tissue dissociation
- Cell isolation in combination with Collagenase NB 1 Premium Grade or another Collagenase NB product
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NB Neutral Protease GMP Grade
Cat. No. 17452.01/ ≥ 2,000 U (PZ) |
- Chromatographically purified and largely free from collagenolytic activity (PZ U) and endotoxins
- Activity (DMC assay) ≥ 0.50 U/mg
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- Tissue dissociation
- Cell isolation in combination with Collagenase NB 1 GMP Grade or Collagenase NB 6 GMP Grade from various tissue types for clinical applications.
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NB Neutral Protease AF GMP Grade
Cat No. 30306.01/ ≥ 2,000 U (PZ) |
- Chromatographically purified and largely free from collagenolytic activity (PZ U) as well as endotoxins
- Absent of any animal-derived ingredients and thorough microbial analysis provide the highest possible safety
- Activity (DMC assay) ≥ 0.50 U/mg
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- Tissue dissociation
- Cell isolation in combination with Collagenase AF-1 GMP Grade from several tissue types for clinical applications
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Collagenase N
Reference Content / ≥ 50 mg
Cat. No. 17463 |
- Class l and ll collagenases and other proteolytic enzymes
- Collagenase activity is regularly reevaluated
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- Reference substance for enzyme activity determination.
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Collagenase N
Reference Identity / ≥ 50 mg
Cat. No. 17464 |
- Class I and ll collagenases and other proteolytic enzymes
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- Reference substance for SDS-PAGE analysis, for incoming goods inspection according to cGMP
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Anti-Collagenase
Cat. No. 58050 / 100 μ |
- Specifically against collagenases from C. histolyticum
- lgG fraction purified by Protein G affinity chromatography
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- Use in ELISA and Western Blot experiments
- Immunostaining of tissue
- Analysis of residual collagenase impurities in cell preparations
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Anti-Collagenase HRP
Cat. No. 58051 / 100 μ |
- Specifically against collagenases from C. histolyticum
- lgG fraction purified by affinity chromatography
- Conjugated with horseradish
- Peroxidase
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- Use in ELISA and Western Blot experiments
- Immunostaining of tissue
- Analysis of residual collagenase impurities in cell preparations
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* PZ activity acc. to Wϋnsch, measured at 25 ° C. |